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Vitamin D May Reduce Fiery Death of Cells and Resulting Severe Inflammation

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Vitamin D May Reduce Fiery Death of Cells and Resulting Severe Inflammation Vitamin D receptor activation leads to reduced pyroptosis, and a shift towards autophagy and apoptosis. Let's review the mechanism of pyroptosis and the studies about vitamin D's role in preventing pyroptosis. Want to get access to DrBeen at low price of $4.99/month? Click here: https://www.drbeen.com/med-nerd/ Want to support this work?: Buy me a coffee :-) https://www.buymeacoffee.com/DrMobeenSyed Become my patron: https://www.patreon.com/mobeensyed?fan_landing=true PayPal: https://paypal.me/mobeensyed?locale.x=en_US My substack: https://mobeensyedmd.substack.com/ #drbeen #Inflammation #VitaminD Disclaimer: This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional. URL list from Friday, Jun. 21 2024 16:18 PM Autophagy, Pyroptosis, and Ferroptosis: New Regulatory Mechanisms for Atherosclerosis - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8793783/ Vitamin D/VDR attenuate cisplatin-induced AKI by down-regulating NLRP3/Caspase-1/GSDMD pyroptosis pathway - ScienceDirect https://www.sciencedirect.com/science/article/abs/pii/S0960076020303149 Vitamin D Receptor Inhibits NLRP3 Activation by Impeding Its BRCC3-Mediated Deubiquitination - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904361/ Pyroptosis: mechanisms and diseases | Signal Transduction and Targeted Therapy https://www.nature.com/articles/s41392-021-00507-5 Effects of Vitamin D3 Supplementation and Aerobic Training on Autophagy Signaling Proteins in a Rat Model Type 2 Diabetes Induced by High-Fat Diet and Streptozotocin - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535215/ Apoptosis Induced by Vitamin D Compounds in Breast Cancer Cells Is Inhibited by Bcl-2 but Does Not Involve Known Caspases or p531 | Cancer Research | American Association for Cancer Research https://aacrjournals.org/cancerres/article/59/19/4848/505530/Apoptosis-Induced-by-Vitamin-D-Compounds-in-Breast Morphological Features of Organelles during Apoptosis: An Overview - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972681/

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1960S SCHLEY RIDE TO EUROPE I LONDON DUBLIN BELFAST GERMANY XD51264

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,Join this channel to get access to perks: https://www.youtube.com/channel/UCddem5RlB3bQe99wyY49g0g/join Want to learn more about Periscope Film and get access to exclusive swag? Join us on Patreon. Visit https://www.patreon.com/PeriscopeFilm Visit our website www.PeriscopeFilm.com This late 1960s travelog film by Norman Schley, a filmmaker from Waukesha, Wisconsin USA, who made a series of amateur films under the moniker "Schley Ride" and/or "Picturelogue inc." This particular account is the first film in a two-part series about a journey through western Europe. This installment highlights the cultural and architectural wonders of London, Dublin, Belfast, and some German cities like East and West Berlin, Cologne, and Frankfurt. The film consists of a montage of clips taken from car, plane, and train windows. Travel pamphlet: “Come to Britain” (0:47). Map highlighting Ireland, the UK, France, Germany, Italy, Austria, Scandinavia (0:49). Pamphlet: “London” and The Big Ben (1:10). The River Thames (1:27). Fleet Street in London (1:31). St. Paul’s Cathedral (1:33). Street scenes, The Underground and double-decker buses (1:36). Leinster Gardens (3:11). Leinster Towers (3:19). Baker Street, London (3:30). Buckingham Palace (3:37). Victoria Memorial (3:52). Changing of the guard (3:59). Westminster Abbey (5:14). The Palace of Westminster (5:34). Tower Bridge (5:38). Guided tour of Tower of London and cannons made in Horsmonden (6:11). Beauchamp Tower (7:04). Yeoman Warder of Tower of London (7:23). St. Paul’s Churchyard (7:46). All-seeing eye mosaic of Freemasons’ Hall (8:37). Piccadilly Circus and Bovril building (8:39). Trafalgar Square (8:48). The Regent’s Park (9:33). Travel route: London to Dublin (10:47). Travel pamphlet “Ireland” (10:52). O'Connell Street and sign for Guinness (10:56). Wellington Monument (11:59). Cows (12:20). Kids ride horses (12:37). Corkagh Park (12:45). Corkagh Park Cycle Track (12:59). Phoenix Park Deer (14:04). Field hockey players (14:08). Netball game (14:45). Brick row-houses (15:19). River LIffey (15:46). Dublin Townhouse (15:58). Perhaps the Old Irish Parliament Building (16:03). Dublin Port - export of barrels of Guinness (16:38). Irish Parliament House (17:16). Christ Church Cathedral (17:17). Kennedy (Peter Kennedy Ltd.) name-owned storefronts (17:43). American Embassy in Dublin (18:21). Hotel Riu Plaza The Gresham Dublin (18:27). Sandymount Beach (18:38). Irish Country roads (18:56). Guinness Lake (19:16). Flora of Irish countryside (19:50). Route: Dublin to Belfast (19:53). Views from train between Dublin and Belfast (19:59). Perhaps Royal Avenue (21:11). Donegal Place and Parliament (21:17). Street scenes of downtown Belfast (21:32). Irish Linen House storefront (22:01). Belfast Castle (22:31). Down Cathedral (22:40). Rural Northern Ireland (23:02). Giant’s Causeway (23:23). Cliffs of Fairhead (24:06). Farm life (24:20). Town of Ballycastle (24:39). Ballycastle bowling club (24:50). Route: Hamburg to Berlin (25:43). Buildings of Berlin (25:59). The Spree River (26:23). Matthäikirchplatz (26:34). Perhaps one of the Kulturforum buildings in West Berlin (26:48). St. Matthew Church (27:01). Kaiser Wilhelm Memorial Church (28:40). The Victory Column (29:23). Kranzler Eck Berlin (29:31). Hertz Rental Car (29:51). Lights of businesses at night (29:56). Bosch (30:27). Mercedes-Benz (30:30). Berlin Airlift Memorial in Platz der Luftbrücke, Tempelhof (31:08). Mayor Willy Brandt (31:56). Berlin Wall (33:14). American sector West Berlin (33:24). US Army Checkpoint Charlie (34:42). Brandenburg Gate (34:51). Reichstag Building (35:22). Berlin Friedrichstraße Station (36:03). Destroyed Berlin Cathedral (36:34). Soviet War Memorial in Treptower Park (36:47). Route: Berlin to Cologne (37:02). Downtown Cologne at dusk (37:17). Cologne Cathedral (37:22). Route: Cologne to Wesbaden to Frankfurt (38:03). Main River and Deutschherren Bridge (38:08). Cologne - Dusseldorf ferry (38:14). Ferry cruise on the Rhine (38:18). Grain silo - Plange Muhle campus (38:38). Köln-Bonner Eisenbahnen AG (KBE) (38:58). Bonn, Germany (39:28). Linz, Germany (40:12). Perhaps Rheinstein Castle (42:15). Perhaps Sooneck Castle (43:06). Perhaps Katz and Maus Castles (43:28). Frankfurt, Germany (44:29). Frankfurt Am Main tram network (45:17). Parkhaus Hirschgraben (45:33). Frankfurt Intercontinental (45:46). St. Nicholas Church (45:54). Europcar rental (46:13). Goethe-Museum (46:16). Justitia Sculpture, Romerberg Square (46:45). Facade of Romer building (47:03). Frankfurt Cathedral spire (48:22). We encourage viewers to add comments and, especially, to provide additional information about our videos by adding a comment! This film is part of the Periscope Film LLC archive, one of the largest historic military, transportation, and aviation stock footage collections in the USA. Entirely film backed, this material is available for licensing in 24p HD, 2k and 4k. For more information visit http://www.PeriscopeFilm.com

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Vitamin D May Reduce Fiery Death of Cells and Resulting Severe Inflammation

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,Vitamin D May Reduce Fiery Death of Cells and Resulting Severe Inflammation Vitamin D receptor activation leads to reduced pyroptosis, and a shift towards autophagy and apoptosis. Let's review the mechanism of pyroptosis and the studies about vitamin D's role in preventing pyroptosis. Want to get access to DrBeen at low price of $4.99/month? Click here: https://www.drbeen.com/med-nerd/ Want to support this work?: Buy me a coffee :-) https://www.buymeacoffee.com/DrMobeenSyed Become my patron: https://www.patreon.com/mobeensyed?fan_landing=true PayPal: https://paypal.me/mobeensyed?locale.x=en_US My substack: https://mobeensyedmd.substack.com/ #drbeen #Inflammation #VitaminD Disclaimer: This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional. URL list from Friday, Jun. 21 2024 16:18 PM Autophagy, Pyroptosis, and Ferroptosis: New Regulatory Mechanisms for Atherosclerosis - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8793783/ Vitamin D/VDR attenuate cisplatin-induced AKI by down-regulating NLRP3/Caspase-1/GSDMD pyroptosis pathway - ScienceDirect https://www.sciencedirect.com/science/article/abs/pii/S0960076020303149 Vitamin D Receptor Inhibits NLRP3 Activation by Impeding Its BRCC3-Mediated Deubiquitination - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904361/ Pyroptosis: mechanisms and diseases | Signal Transduction and Targeted Therapy https://www.nature.com/articles/s41392-021-00507-5 Effects of Vitamin D3 Supplementation and Aerobic Training on Autophagy Signaling Proteins in a Rat Model Type 2 Diabetes Induced by High-Fat Diet and Streptozotocin - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535215/ Apoptosis Induced by Vitamin D Compounds in Breast Cancer Cells Is Inhibited by Bcl-2 but Does Not Involve Known Caspases or p531 | Cancer Research | American Association for Cancer Research https://aacrjournals.org/cancerres/article/59/19/4848/505530/Apoptosis-Induced-by-Vitamin-D-Compounds-in-Breast Morphological Features of Organelles during Apoptosis: An Overview - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972681/

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,Want to support this channel and help us preserve old films? Visit https://www.patreon.com/PeriscopeFilm Visit our website www.PeriscopeFilm.com This 1960 color documentary film from Convair Astronautics Division and General Dynamics Corporation uses montage and bold narration to dramatise the feats of collaborative engineering and technological advancement behind the SM-65 Atlas intercontinental ballistic missile, a success for the United States in the late 1950s, during the Cold War’s “Space Race” with the Soviet Union. This film features the launch of SM-65B, rocket 4B on August 2, 1958. It was the second model of the second prototype version, which introduced a stage and a half system and was the first American rocket to achieve the distinction of being truly intercontinental in range (TRT: 27:28). Opening titles: “On Target” over a monitor display resembling a flatlining EKG. A rotating beacon light (0:09). A man in silhouette smokes a cigarette. A hearse-like station wagon pulls away from a parking lot, followed by a “Leonard Bros.” truck hauling a covered ICBM (0:25). The two vehicles on the road, destined for Cape Canaveral, Florida. Driving through snow (1:17). Arriving at “Convair Astronautics” (1:59). The Florida headquarters of the “Air Force Missile Test Center.” Exterior “AFMTC Central Control Blvd.” Satellite dish antennas and a waving U.S. flag. (2:31). Antennas of the AZUSA ground-based radar tracking system at the Air Force Eastern Test Range. Telemetry antennas rotate into position (3:12). An Atlas ICBM erected in a Cape Canaveral launch service tower. Pan across clouds (3:37). A control tower on the island of San Salvador. A sign alongside a doorway: “Central Control.” Inside, engineers and flight controllers speak on radio headsets (4:03). Outdoors, various antennas rotate into position, taking readings (4:43). Spinning memory reels of magnetic tape record data. Engineers plot the course of the Atlas on instrument panels (5:17). Station 9A at Antigua in the Caribbean. A Kennedy high-gain antenna (HGA) and a receiver building (6:34). A meteorologist releases a weather balloon (7:48). A ship at sea acts as a mobile tracking station near Trinidad. An engineer uses a radar system (8:17). A jeep at Antigua’s station. Inside, engineers put on headsets and speak, flipping switches (9:05). Cargo is unloaded from a ship and into a truck (10:04). A U.S. Air Force jet airliner takes off. Aerial photography of a control tower (10:46). Pad 13 at Cape Canaveral. The rocket payload is hoisted into position. Closeups on engineers wearing sunglasses, hardhats (11:46). The nose cone data capsule (12:24). Mission control. Engineers speak on telephones. A telemetering trailer: “Authorized Personnel Only” (12:43). Blips pulse on a radar monitor (13:18). Magnetic memory reels (13:37). Launch day. Closeup on the rocket “4B” at Cape Canaveral Launch Complex 13 (13:50). The service tower retracts, exposing the gleaming rocket (14:23). A digital clock counts down. Men wait with anticipation in control rooms (15:39). Storm clouds gather and thunder is heard (16:17). A delay is encountered (17:15). Cameras rotate into position. The test area is evacuated (17:45). A montage of instrument panels, employees, and support aircraft at the ready. Clear skies prevail (19:01). All systems are “go” with 4 minutes until launch (20:04). A General Electric console. Switches are flipped. A periscope viewer is checked (21:03). The rocket is all clear, as the final supports are released (21:36). The final countdown (22:15). The Atlas rocket’s engine ignites. Blastoff. The rocket takes off. An observatory dome tracks its flight (22:38). A tracking map charts the flight of the Atlas ICBM (23:55). Quiet at mission control. Radar antennas maneuver. Data printouts continue. The rocket continues “off the charts” (24:53). The launch crew celebrates the news that the nose cone has separated successfully (25:56). The narrator boasts of a direct hit on a target in the Atlantic Ocean and the possibility of “instant retaliation” (26:45). End titles (27:14). We encourage viewers to add comments and, especially, to provide additional information about our videos by adding a comment! See something interesting? Tell people what it is and what they can see by writing something for example: "01:00:12:00 -- President Roosevelt is seen meeting with Winston Churchill at the Quebec Conference." This film is part of the Periscope Film LLC archive, one of the largest historic military, transportation, and aviation stock footage collections in the USA. Entirely film backed, this material is available for licensing in 24p HD, 2k and 4k. For more information visit http://www.PeriscopeFilm.com

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