,,-gsLxPagNB8,UCrtd2wePvAl6RN_D-9jWVQQ, Health,Knowledge, channel_UCrtd2wePvAl6RN_D-9jWVQQ, video_-gsLxPagNB8,What Are Reactive Oxygen Species and Lipid Species?
Let's understand the foundational components of inflammation reactive oxygen and reactive lipid species.
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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
,,hRCac7xcAtg,UCrtd2wePvAl6RN_D-9jWVQQ, Health, channel_UCrtd2wePvAl6RN_D-9jWVQQ, video_hRCac7xcAtg,Erratum: Quercetin is primarily lipid soluble and weakly water soluble. I have put it in an incorrect category.
Which Antioxidants To Use Together?
As we use antioxidants for aches and pains/inflammation we need to keep in mind the water or lipid solubility of the molecule. Let's review.
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,1,Simple Plan to Control Inflammation
Here is an important list of anti-inflammatory molecules to help manage inflammation.
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#drbeen #Inflammation #Supplements
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
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References:
Visit articles related to these topics and see the references at the end: https://www.drbeen.com/articles/category/chronic-inflammation/
,1,Vitamin D May Reduce Fiery Death of Cells and Resulting Severe Inflammation
Vitamin D receptor activation leads to reduced pyroptosis, and a shift towards autophagy and apoptosis. Let's review the mechanism of pyroptosis and the studies about vitamin D's role in preventing pyroptosis.
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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
URL list from Friday, Jun. 21 2024 16:18 PM
Autophagy, Pyroptosis, and Ferroptosis: New Regulatory Mechanisms for Atherosclerosis - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8793783/
Vitamin D/VDR attenuate cisplatin-induced AKI by down-regulating NLRP3/Caspase-1/GSDMD pyroptosis pathway - ScienceDirect
https://www.sciencedirect.com/science/article/abs/pii/S0960076020303149
Vitamin D Receptor Inhibits NLRP3 Activation by Impeding Its BRCC3-Mediated Deubiquitination - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904361/
Pyroptosis: mechanisms and diseases | Signal Transduction and Targeted Therapy
https://www.nature.com/articles/s41392-021-00507-5
Effects of Vitamin D3 Supplementation and Aerobic Training on Autophagy Signaling Proteins in a Rat Model Type 2 Diabetes Induced by High-Fat Diet and Streptozotocin - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535215/
Apoptosis Induced by Vitamin D Compounds in Breast Cancer Cells Is Inhibited by Bcl-2 but Does Not Involve Known Caspases or p531 | Cancer Research | American Association for Cancer Research
https://aacrjournals.org/cancerres/article/59/19/4848/505530/Apoptosis-Induced-by-Vitamin-D-Compounds-in-Breast
Morphological Features of Organelles during Apoptosis: An Overview - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972681/
,1,Omega-3 Reduces Chronic Inflammation and Neurosurgical Pain
Two studies demonstrating the power of omega-3 to reduce inflammation and neurosurgical pain.
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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
Reference:
Omega-3 fatty acids (fish oil) as an anti-inflammatory: an alternative to nonsteroidal anti-inflammatory drugs for discogenic pain - PubMed https://pubmed.ncbi.nlm.nih.gov/16531187/
An Oily Fish Diet Improves Subclinical Inflammation in People at High Cardiovascular Risk: A Randomized Controlled Study - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199776/
Study Details | Effects of Dietary Polyphenols and ω-3 Fatty Acids on Cardiovascular Risk Factors in High Risk Subjects | ClinicalTrials.gov https://clinicaltrials.gov/study/NCT01154478
Table - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199776/table/molecules-26-03369-t001/
University of Naples Federico II - Wikipedia https://en.wikipedia.org/wiki/University_of_Naples_Federico_II
,1,Omega-3 Reduces Chronic Inflammation
In this study from Federico University Italy researchers demonstrate how omega-3 and vitamin D reduce inflammatory markers.
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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
Reference:
An Oily Fish Diet Improves Subclinical Inflammation in People at High Cardiovascular Risk: A Randomized Controlled Study - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199776/
Study Details | Effects of Dietary Polyphenols and ω-3 Fatty Acids on Cardiovascular Risk Factors in High Risk Subjects | ClinicalTrials.gov https://clinicaltrials.gov/study/NCT01154478
Table - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199776/table/molecules-26-03369-t001/
University of Naples Federico II - Wikipedia https://en.wikipedia.org/wiki/University_of_Naples_Federico_II
Omega-3 fatty acids (fish oil) as an anti-inflammatory: an alternative to nonsteroidal anti-inflammatory drugs for discogenic pain - PubMed https://pubmed.ncbi.nlm.nih.gov/16531187/
,1,6/13/2024 - Paul Bork Presents COVID Stats
Our Paul Bork is presenting COVID Stats and some more topics today. Let's listen in.
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,1,Understanding Inflammatory Pathways and How Supplements Can Help
In this video, we dive into the fascinating world of inflammation and explore the main pathways that play a crucial role in the body's response to injury or infection. We discuss the:
My article capturing this information: https://www.drbeen.com/articles/understanding-inflammatory-pathways-and-how-supplements-can-help/
Following pathways and supplements to modulate these are presented in this talk:
Arachidonic Acid Pathway
JAK-STAT Pathway
MAPK Pathway
NF-κB Pathway
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Disclaimer:
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Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
Timestamps:
0:00 - Introduction to Inflammatory Pathways
0:34 - Pathways
2:39 - Supplements
Further Reading and References:
NF-kB and Jak-STAT pathway suppression
Anti-inflammatory effect of resveratrol through the suppression of NF-κB and JAK/STAT signaling pathways | Acta Biochimica et Biophysica Sinica | Oxford Academic
https://academic.oup.com/abbs/article/47/3/207/1754742
Curcumin Regulates Anti-Inflammatory Responses by JAK/STAT/SOCS Signaling Pathway in BV-2 Microglial Cells - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784227/
Potential therapeutic effects of curcumin mediated by JAK/STAT signaling pathway: A review - PubMed
https://pubmed.ncbi.nlm.nih.gov/32157749/
Curcumin Blocks Cytokine-Mediated NF-κB Activation and Proinflammatory Gene Expression by Inhibiting Inhibitory Factor I-κB Kinase Activity1 | The Journal of Immunology | American Association of Immunologists
https://journals.aai.org/jimmunol/article/163/6/3474/32577/Curcumin-Blocks-Cytokine-Mediated-NF-B-Activation
Inhibitory effect of green tea extract on β-amyloid-induced PC12 cell death by inhibition of the activation of NF-κB and ERK/p38 MAP kinase pathway through antioxidant mechanisms - ScienceDirect
https://www.sciencedirect.com/science/article/abs/pii/S0169328X05002998
Arachidonic Acid Pathway
Omega-3 PUFAs Lower the Propensity for Arachidonic Acid Cascade Overreactions - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537720/
MAPK Pathway
Omega-3 fatty acids mediated Cellular signaling and its regulation in Human Health - ScienceDirect
https://www.sciencedirect.com/science/article/pii/S266726852300058X
Inhibitory effect of green tea extract on β-amyloid-induced PC12 cell death by inhibition of the activation of NF-κB and ERK/p38 MAP kinase pathway through antioxidant mechanisms - ScienceDirect
https://www.sciencedirect.com/science/article/abs/pii/S0169328X05002998
,1,Pancreatic Cancer Vaccines With Amazing Results in Phase I
Pancreatic ductal adenocarcinoma is one of the most lethal cancers with a 5 year survival rate of less than 10%. mRNA designer/personalized vaccines are changing this situation. Let's review the results of phase I trials.
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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
URL list from Tuesday, Jun. 4 2024 11:37 AM
Pancreatic ductal adenocarcinoma: biological hallmarks, current status, and future perspectives of combined modality treatment approaches | Radiation Oncology | Full Text
https://ro-journal.biomedcentral.com/articles/10.1186/s13014-019-1345-6
NHS England Thousands of NHS patients to access trials of personalised cancer ‘vaccines’
https://www.england.nhs.uk/2024/05/thousands-of-nhs-patients-to-access-trials-of-personalised-cancer-vaccines/
Three-year Phase 1 Follow-Up Data for mRNA-based Individualized Immunotherapy Candidate Show Persistence of Immune Response and Delayed Tumor Recurrence in Some Patients with Resected Pancreatic Cancer | BioNTech
https://investors.biontech.de/news-releases/news-release-details/three-year-phase-1-follow-data-mrna-based-individualized
Investigational mRNA Vaccine Induced Persistent Immune Response in Phase 1 Trial of Patients With Pancreatic Cancer | Memorial Sloan Kettering Cancer Center
https://www.mskcc.org/news/can-mrna-vaccines-fight-pancreatic-cancer-msk-clinical-researchers-are-trying-find-out
Trial Design
https://www.biontech.com/int/en/home/pipeline-and-products/clinical-trials-new/trial-design.html
Cancer vaccines are having a renaissance | MIT Technology Review
https://www.technologyreview.com/2024/05/03/1092026/cancer-vaccines-are-having-a-renaissance/
NHS England launches scheme to boost signups for personalised cancer vaccine trials | The BMJ
https://www.bmj.com/content/385/bmj.q1212#:~:text=The%20vaccines%20currently%20being%20trialled,identify%20and%20destroy%20cancer%20cells.
,1,Make Life Difficult for People
Interesting thought by Dr. Fauci about forcing people to get vaccinated. "Make it difficult in their lives and they will lose their ideological bullshit." - Fauci. Let's hear.
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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
Reference:
Time stamp: 2:45:03 in the video
https://www.youtube.com/live/nvQTXAgtA6s?si=_5lmhhz_B5vhihSu&t=9903
Vaccinations
https://travel.state.gov/content/travel/en/us-visas/immigrate/vaccinations.html
COVID-19 international travel advisories | USAGov
https://www.usa.gov/covid-international-travel#:~:text=Visitors%20to%20the%20U.S.%20do,the%20country%20you%20will%20visit.
(18) Te𝕏asLindsay™ on X: "A U.S. Citizen living abroad reached out & asked for help to shine a light on what’s preventing him from legally returning to the U.S. from Japan with his beautiful little family. He’s not alone—this problem is impacting U.S. Citizens & their families around the world. 1/🧵 https://t.co/zl5uqMNzGN" / X
https://x.com/TexasLindsay_/status/1793283248971305288/photo/1
Executive Order on Moving Beyond COVID-19 Vaccination Requirements for Federal Workers | The White House
https://www.whitehouse.gov/briefing-room/presidential-actions/2023/05/09/executive-order-on-moving-beyond-covid-19-vaccination-requirements-for-federal-workers/
CDC Museum COVID-19 Timeline | David J. Sencer CDC Museum | CDC
https://www.cdc.gov/museum/timeline/covid19.html
Statewide COVID‐19 Stay‐at‐Home Orders and Population Mobility in the United States - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7405141/
,1,Taurine Talk with Dr. Vijay K. Yadav
According to a new study involving mice, non-human primates, and humans; taurine supplementation extends healthy lifespan. Let's speak with Vijay K. Yadav who is one of the researchers.
Vijay's Brief Biography
Vijay K. Yadav (born 1977) is an American biologist and biogerontologist. He is currently a faculty at the Vagelos College of Physicians and Surgeons at Columbia University. Overarching theme of Dr. Yadav’s laboratory is to investigate how (semi)essential nutrients regulate whole-body homeostasis, and how this process gets dysregulated during aging to identify novel avenue to treat diseases of aging. His research in the last two decades has shown that self-imposed domestication in humans has led to an imbalance in nutrient-genetic interactions leading to increased incidence of diseases. Dr. Yadav is best known for his research on evolutionarily conserved mechanisms of aging, in particular on how nutrients such as vitamin B12 and taurine regulate aging.
Where to find Dave:
LinkedIn: https://www.linkedin.com/in/drvijaykyadav
Twitter: https://twitter.com/VijayYadavLab
Lab website: https://sites.google.com/view/systems-biology-of-aging-lab/home
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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
URL list from Friday, Feb. 2 2024 11:10 AM
Taurine deficiency as a driver of aging - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630957/
Citation:
Singh P, Gollapalli K, Mangiola S, Schranner D, Yusuf MA, Chamoli M, Shi SL, Lopes Bastos B, Nair T, Riermeier A, Vayndorf EM, Wu JZ, Nilakhe A, Nguyen CQ, Muir M, Kiflezghi MG, Foulger A, Junker A, Devine J, Sharan K, Chinta SJ, Rajput S, Rane A, Baumert P, Schönfelder M, Iavarone F, di Lorenzo G, Kumari S, Gupta A, Sarkar R, Khyriem C, Chawla AS, Sharma A, Sarper N, Chattopadhyay N, Biswal BK, Settembre C, Nagarajan P, Targoff KL, Picard M, Gupta S, Velagapudi V, Papenfuss AT, Kaya A, Ferreira MG, Kennedy BK, Andersen JK, Lithgow GJ, Ali AM, Mukhopadhyay A, Palotie A, Kastenmüller G, Kaeberlein M, Wackerhage H, Pal B, Yadav VK. Taurine deficiency as a driver of aging. Science. 2023 Jun 9;380(6649):eabn9257. doi: 10.1126/science.abn9257. Epub 2023 Jun 9. PMID: 37289866; PMCID: PMC10630957.
,1,Oreo Cookies Reduce LDL More Than Statins
In a recent study researchers found that some individuals are lean mass hyper-responders (LMHR). In these individuals ketogenic diet increases LDL levels, and taking carbs reduces LDL more than statins. Let's review this phenomenon with Dave Feldman - the person who discovered this phenotype and explore various studies that their team have conducted.
Dave's Bio:
Dave Feldman is a software and platform engineer, an entrepreneur, and founder of the Citizen Science Foundation. His life took a radical turn on seeing his cholesterol skyrocket after adopting a ketogenic diet and became obsessed with understanding why this is common with those who are likewise leaner and more metabolically healthy. On researching lipidology, he found the system the human body utilizes to manage cholesterol in the blood closely resembles a network, much like those he's worked on in engineering. Through a series of self experiments and partnering with formal researchers, he has since published the "Lipid Energy Model" which may explain this phenomenon. In addition to this mechanistic research, he's now spearheading a study out of UCLA that will gather advanced heart scans (CCTA) on participants with a likewise high LDL cholesterol and whether it will be associated with high risk for cardiovascular disease.
Where to find Dave:
https://twitter.com/realDaveFeldman
https://youtube.com/@realDaveFeldman
https://instagram.com/realDaveFeldman
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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
,1,Treatment Resistant Depression? This Study Provides an Answer
In this study from the United Kingdom the researchers demonstrate that the treatment resistant depression patients responded well to the transcranial magnetic stimulation. The improvement in 20% of the patients were up to six months and in another 20% complete remission was achieved. Let's review this study together.
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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
URL list from Friday, Jan. 26 2024 15:33 PM
Connectivity-guided intermittent theta burst versus repetitive transcranial magnetic stimulation for treatment-resistant depression: a randomized controlled trial | Nature Medicine
https://www.nature.com/articles/s41591-023-02764-z?utm_medium=affiliate&utm_source=commission_junction&utm_campaign=CONR_PF018_ECOM_GL_PHSS_ALWYS_DEEPLINK&utm_content=textlink&utm_term=PID100032693&CJEVENT=16b926adbc7c11ee8271005f0a1eba23
Transcranial Magnetic Stimulation - Physiopedia
https://www.physio-pedia.com/Transcranial_Magnetic_Stimulation
Default mode network - Wikipedia
https://en.wikipedia.org/wiki/Default_mode_network
,1,COVID Stats with Paul Bork
Our resident statistician Paul Bork discusses the new variants and their impact. Let's listen in.
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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
,1,Montana Law Restricting Vaccine Status Query is in Appellate Court
Montana's law to restrict queries about a patient or staff's vaccine status was permanently banned by the district court. However, this decision is now in 9th circuit court of appeals. Let's quickly review.
I am not a lawyer, this is not a legal advice. Just a review of the reporting.
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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
URL list from Sunday, Jan. 21 2024
HB0702.pdf
https://leg.mt.gov/bills/2021/billpdf/HB0702.pdf
COVID-19: Employment Law and Developments Tracker | Practical Law
https://content.next.westlaw.com/practical-law/document/I6c41215f69d111eaadfea82903531a62/COVID-19-Employment-Law-and-Developments-Tracker?viewType=FullText&transitionType=Default&contextData=(sc.Default)
Federal judge strikes down Montana vaccine choice law in health care settings
https://montanafreepress.org/2022/12/09/federal-judge-strikes-down-montana-vaccine-choice-law-in-health-care-settings/
Montana only state to ban vaccine requirements for employees | AP News
https://apnews.com/article/business-health-coronavirus-pandemic-montana-8c47ca9308494b678f41f41764094800
Court stops law that barred vaccine status queries—for all vaccines | American Medical Association
https://www.ama-assn.org/delivering-care/public-health/court-stops-law-barred-vaccine-status-queries-all-vaccines
Montana vaccine law would put physicians in ethical bind | American Medical Association
https://www.ama-assn.org/delivering-care/public-health/montana-vaccine-law-would-put-physicians-ethical-bind
,1,Supreme Court Vacates Rulings Against Vaccine Mandates
On December 11th 2023 supreme court vacated the cases against the Biden Administration for vaccine mandates. Let's review the reporting.
I am not a lawyer, this is not a legal advice. Just a review of the reporting.
#drbeen #koolbeens #COVID
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
Supreme Court vacates ruling restricting president's right to issue federal workforce mandates - Government Executive
https://www.govexec.com/workforce/2023/12/supreme-court-vacates-ruling-restricting-presidents-right-issue-federal-workforce-mandates/392636/
Supreme Court wipes rulings on federal employee, military vaccine mandates | The Hill
https://thehill.com/policy/healthcare/4353550-supreme-court-wipes-rulings-federal-employee-military-vaccine-mandates/
Covid-19 vaccine mandates for executive branch employees and troops thrown out by Supreme Court | CNN Politics
https://www.cnn.com/2023/12/11/politics/supreme-court-throws-out-cases-over-federal-covid-19-vaccine-mandates-for-executive-branch-employees-and-troops/index.html
U.S. Court of Appeals - D.C. Circuit - Home
https://www.cadc.uscourts.gov/internet/home.nsf
United States Court of Appeals for the District of Columbia Circuit - Ballotpedia
https://ballotpedia.org/United_States_Court_of_Appeals_for_the_District_of_Columbia_Circuit#:~:text=The%20United%20States%20Court%20of,Court%20of%20the%20United%20States.
District of Columbia (until 1871) - Wikipedia
https://en.wikipedia.org/wiki/District_of_Columbia_(until_1871)
United States Court of Appeals for the Fifth Circuit - Wikipedia
https://en.wikipedia.org/wiki/United_States_Court_of_Appeals_for_the_Fifth_Circuit
,1,Mitochondria and Aging
In this amazing study the researchers provide the evidence that mitochondrial membrane permeability plays an important role in cell senescence and death. We will use these concepts for the next series about Taurin. Let's review at a high level the study about mitochondria and aging.
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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
URL list from Friday, Jan. 19 2024 14:13 PM
Aging? Blame your mitochondria - Science in the News
https://sitn.hms.harvard.edu/flash/2023/aging-blame-your-mitochondria/
Apoptotic stress causes mtDNA release during senescence and drives the SASP | Nature
https://www.nature.com/articles/s41586-023-06621-4#Sec8
Mitochondrial dysfunction in cell senescence and aging - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246372/
Mitochondrial and metabolic dysfunction in ageing and age-related diseases | Nature Reviews Endocrinology
https://www.nature.com/articles/s41574-021-00626-7
Pleiotropic effects of mitochondria in aging | Nature Aging
https://www.nature.com/articles/s43587-022-00191-2
Bax, Bak and beyond - mitochondrial performance in apoptosis - PubMed
https://pubmed.ncbi.nlm.nih.gov/28755482/
The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166495/
,1,Long COVID - Muscle Fatigue | Muscle Fiber Type Shift is Possible
Following up on our last video about the muscle fiber type shift in long COVID patients. In this talk I have discussed the evidence that shows that the muscle fiber type can be switched from glycolytic to oxidative and vice versa. And, not only the fiber type switching can occur but mitochondria can also be increased. Let's review.
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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
URL list from Monday, Jan. 15 2024
DrBeen.Com
https://members.drbeen.com/
Study that needed further explaination: Muscle abnormalities worsen after post-exertional malaise in long COVID | Nature Communications
https://www.nature.com/articles/s41467-023-44432-3
References for the muscle fiber type shifts:
Mixing it up: the biological significance of hybrid skeletal muscle fibers - PubMed
https://pubmed.ncbi.nlm.nih.gov/31784473/
Mixing it up: the biological significance of hybrid skeletal muscle fibers | Journal of Experimental Biology | The Company of Biologists
https://journals.biologists.com/jeb/article/222/23/jeb200832/223582/Mixing-it-up-the-biological-significance-of-hybrid
Muscle Fiber Type Transitions with Exercise Training: Shifting Perspectives - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473039/
Changes in myosin heavy chain mRNA and protein expression in human skeletal muscle with age and endurance exercise training - PubMed
https://pubmed.ncbi.nlm.nih.gov/15746299/
Exercise-induced mitochondrial biogenesis begins before the increase in muscle PGC-1alpha expression - PubMed
https://pubmed.ncbi.nlm.nih.gov/17099248/
Recent Perspectives Regarding the Role of Dietary Protein for the Promotion of Muscle Hypertrophy with Resistance Exercise Training - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852756/
Effects of Qigong exercise on muscle strengths and oxidative stress/antioxidant responses in young sedentary females: a quasi-experimental study - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7609847/
,1,Muscle Abnormalities Worsen in Post Exertional Malaise
In this amazing study the Dutch researchers used muscle biopsies in the long COVID patients suffering from post-exertional malaise. They found that the muscle phenotype had changed resulting in lower excercise capacity. They also found mitochondrial function issues, and local amyloid accumulation. Macrophages and CD3+ T cells were also infiltrated in the muscle tissues. Let's review.
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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
Muscle abnormalities worsen after post-exertional malaise in long COVID - Nature Communications
https://www.nature.com/articles/s41467-023-44432-3
A discovery in the muscles of long COVID patients may explain exercise troubles
https://www.npr.org/sections/health-shots/2024/01/09/1223077307/long-covid-exercise-post-exertional-malaise-mitochondria
A central role for amyloid fibrin microclots in long COVID/PASC: origins and therapeutic implications - PubMed
https://pubmed.ncbi.nlm.nih.gov/35195253/
Amyloidosis: Definition of Amyloid and Amyloidosis, Classification Systems, Systemic Amyloidoses
https://emedicine.medscape.com/article/335414-overview
Treating the Most Disruptive Symptoms First and Preventing Worsening of Symptoms | Clinical Care of Patients | Healthcare Providers | Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) | CDC
https://www.cdc.gov/me-cfs/healthcare-providers/clinical-care-patients-mecfs/treating-most-disruptive-symptoms.html
Muscle Fatigue: Lactic Acid or Inorganic Phosphate the Major Cause? | Physiology
https://journals.physiology.org/doi/full/10.1152/physiologyonline.2002.17.1.17#:~:text=Intracellular%20acidosis%20due%20mainly%20to,cause%20of%20skeletal%20muscle%20fatigue.
Science Fact or Science Fiction? Lactic Acid Buildup Causes Muscle Fatigue and Soreness | Pfizer
https://www.pfizer.com/news/articles/science_fact_or_science_fiction_lactic_acid_buildup_causes_muscle_fatigue_and_soreness
Glycolysis - Wikipedia
https://en.wikipedia.org/wiki/Glycolysis
Human Skeletal Muscle Fiber Type Classifications
https://academic.oup.com/ptj/article/81/11/1810/2857618
Muscle Fiber Type Transitions with Exercise Training: Shifting Perspectives
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473039/
Muscle Hypertrophy - an overview | ScienceDirect Topics
https://www.sciencedirect.com/topics/medicine-and-dentistry/muscle-hypertrophy
Muscle abnormalities worsen after post-exertional malaise in long COVID - Nature Communications
https://www.nature.com/articles/s41467-023-44432-3
A discovery in the muscles of long COVID patients may explain exercise troubles
https://www.npr.org/sections/health-shots/2024/01/09/1223077307/long-covid-exercise-post-exertional-malaise-mitochondria
,1,If you like this content and want more, I am doing a special lifetime membership offer. Click here:
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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
,1,Long COVID Neurological Outcomes and Anti-Idiotype Antibodies with Prof. Dr. William Murphy
Let's review the latest paper by Dr. William Murphy about the anti-Idiotype antibodies and their role in neurological outcomes in long COVID.
Brief bio of Dr. Murphy:
My research for the past 30 years has centered on translational studies involving modeling cancer-immune system interactions starting with my earlier studies on NK cells and HSCT in mouse models and later at the National Cancer Institute on their role in cancer immunotherapy which then expanded to issues in immunotherapy in general.
If you like this content and want more, I am doing a special lifetime membership offer. Click here:
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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
,1,Penile Fractures and More Holiday Injuries
If every day was Christmas there will be 43% more penile fractures. Let's look at this new German study and also be aware of holiday injuries.
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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
URL list from Friday, Dec. 22 2023
DrBeen: Online Personalized Medical Education - DrBeen
https://www.drbeen.com/
Penile Fracture - Clinical Features - Emergency Management - TeachMeSurgery
https://teachmesurgery.com/urology/other/penile-fracture/
Risk of penile fractures rises at Christmas, doctors find | Christmas | The Guardian
https://www.theguardian.com/lifeandstyle/2023/dec/20/risk-of-penile-fractures-rises-at-christmas-doctors-find#:~:text=They%20have%20discovered%20that%20the,during%20over%2Denthusiastic%20sexual%20intercourse.
Penile fractures: the price of a merry Christmas
https://bjui-journals.onlinelibrary.wiley.com/doi/epdf/10.1111/bju.16216
,1,mRNA Vaccines - Researchers Propose A Design Fix
An article on University of Cambridge contains this statement, "Researchers have discovered that misreading of therapeutic mRNAs by the cell’s decoding machinery can cause an unintended immune response in the body. They have identified the sequence within the mRNA that causes this to occur and found a way to prevent ‘off-target’ immune responses to enable the safer design of future mRNA therapeutics."
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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
URL list from Friday, Dec. 8 2023
Researchers redesign future mRNA therapeutics to prevent potentially harmful immune responses | University of Cambridge
https://www.cam.ac.uk/research/news/researchers-redesign-future-mrna-therapeutics-to-prevent-potentially-harmful-immune-responses
N1-methylpseudouridylation of mRNA causes +1 ribosomal frameshifting | Nature
https://www.nature.com/articles/s41586-023-06800-3
The Shape and Structure of Proteins - Molecular Biology of the Cell - NCBI Bookshelf
https://www.ncbi.nlm.nih.gov/books/NBK26830/#:~:text=A%20protein%20molecule%20is%20made,one%20molecule%20to%20the%20next.
Ribosomes, Transcription, Translation | Learn Science at Scitable
https://www.nature.com/scitable/topicpage/ribosomes-transcription-and-translation-14120660/#:~:text=Recall%20that%20mRNA%20molecules%20are,protein%20as%20it%20is%20synthesized.
Genetic code - Wikipedia
https://en.wikipedia.org/wiki/Genetic_code
DNA and RNA codon tables - Wikipedia
https://en.wikipedia.org/wiki/DNA_and_RNA_codon_tables
Pseudouridine - Wikipedia
https://en.wikipedia.org/wiki/Pseudouridine
Modifications in an Emergency: The Role of N1-Methylpseudouridine in COVID-19 Vaccines | ACS Central Science
https://pubs.acs.org/doi/10.1021/acscentsci.1c00197
Ribonucleotide - Wikipedia
https://en.wikipedia.org/wiki/Ribonucleotide#:~:text=In%20biochemistry%2C%20a%20ribonucleotide%20is,monomeric%20building%20blocks%20for%20RNA.
Translation: DNA to mRNA to Protein | Learn Science at Scitable
https://www.nature.com/scitable/topicpage/translation-dna-to-mrna-to-protein-393/#:~:text=The%20process%20of%20translation%20can,transcription%20as%20well%20as%20tRNA.&text=The%20genes%20in%20DNA%20encode,the%20functions%20necessary%20for%20life.
Frontiers | On programmed ribosomal frameshifting: the alternative proteomes
https://www.frontiersin.org/articles/10.3389/fgene.2012.00242/full#:~:text=Frameshifting%20is%20a%20process%20whereby,downstream%20(%E2%88%921%20frameshift).
,1,Cancer Immunotherapy - CAR-T Cells. (Part 3) with Prof. Dr. William Murphy
Dr. William Murphy Distinguished Prof., Vice Chair of Research for Dermatology and Internal Medicine departments discusses cancer immunotherapy. Following topics are discussed:
What are CAR-T cells?
Empowering the T cells and NK cells against cancers.
Engineering CAR-T cells.
Why T cells?
What cells are the sources of CARs?
How CAR are built?
Mechanism of action.
Brief bio of Dr. Murphy:
My research for the past 30 years has centered on translational studies involving modeling cancer-immune system interactions starting with my earlier studies on NK cells and HSCT in mouse models and later at the National Cancer Institute on their role in cancer immunotherapy which then expanded to issues in immunotherapy in general.
If you like this content and want more, I am doing a special lifetime membership offer. Click here:
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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
,1,Pain and Burning Sensations
Some individuals suffering from neuropathic pain experience pins and needles, hot or cold, buzzing, and burning sensations in their body or parts of the body. There are many possibilities for these symptoms, however, in today's talk we will discuss the role of a sensory ganglion pathology with such neuropathic pains.
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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
URL list from Friday, Dec. 1 2023
Neuropathic Pain Associated with COVID-19: a Systematic Review of Case Reports | Current Pain and Headache Reports
https://link.springer.com/article/10.1007/s11916-022-01065-3
Functional Anatomy of the Sensory Nervous System: Updates From the Neuroscience Bench - LaTasha K. Crawford, Michael J. Caterina, 2020
https://journals.sagepub.com/doi/10.1177/0192623319869011
Tissue-resident M2 macrophages directly contact primary sensory neurons in the sensory ganglia after nerve injury - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8513227/
SARS-CoV-2 airway infection results in the development of somatosensory abnormalities in a hamster model | Science Signaling
https://www.science.org/doi/10.1126/scisignal.ade4984
Neuropathic symptoms with SARS-CoV-2 vaccination - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128783/
How Is Peripheral Injury Signaled to Satellite Glial Cells in Sensory Ganglia? - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833977/
Neuron-associated macrophage proliferation in the sensory ganglia is associated with peripheral nerve injury-induced neuropathic pain involving CX3CR1 signaling | eLife
https://elifesciences.org/articles/78515
Neuropathic Pain: From Mechanisms to Treatment | Physiological Reviews
https://journals.physiology.org/doi/full/10.1152/physrev.00045.2019
ILF3 - Wikipedia
https://en.wikipedia.org/wiki/ILF3
Calcitonin gene-related peptide - Wikipedia
https://en.wikipedia.org/wiki/Calcitonin_gene-related_peptide
What are satellite glial cells? — Brain Stuff
https://brainstuff.org/blog/what-are-satellite-glial-cells
Capillaries - Physiopedia
https://www.physio-pedia.com/Capillaries
Mechanics of endothelial cell architecture and vascular permeability - PubMed
https://pubmed.ncbi.nlm.nih.gov/11417757/
Substance P - Wikipedia
https://en.wikipedia.org/wiki/Substance_P
,1,Respiratory Illness in China and More News
Let's review WHO's version of what's going on in China. We will also look at the current variant type, COVID hospitalizations, a study of brain changes in long COVID patients; largest most extensive analysis of background rates of adverse events of interest, and a systematic review of cardiovascular problems after vaccinations.
If you like this content and want more, I am doing a special lifetime membership offer. Click here:
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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
URL list from Thursday, Nov. 30 2023
WHO statement on reported clusters of respiratory illness in children in northern China
https://www.who.int/news/item/22-11-2023-who-statement-on-reported-clusters-of-respiratory-illness-in-children-in-northern-china
Upsurge of respiratory illnesses among children-Northern China
https://www.who.int/emergencies/disease-outbreak-news/item/2023-DON494
COVID variant BA.2.86 triples in new CDC estimates, now 8.8% of cases - CBS News
https://www.cbsnews.com/news/covid-variant-ba-2-86-triples-in-new-cdc-estimates/?ftag=YHF4eb9d17
CDC COVID Data Tracker: Trends by Geographic Area
https://covid.cdc.gov/covid-data-tracker/#trends_currenthospitalizations_select_00
MRI study spotlights impact of long COVID on the brain | CIDRAP
https://www.cidrap.umn.edu/covid-19/mri-study-spotlights-impact-long-covid-brain
Neurite Orientation Dispersion and Density Imaging for Assessing Acute Inflammation and Lesion Evolution in MS - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7963254/
Neurite - Wikipedia
https://en.wikipedia.org/wiki/Neurite
Characterising the background incidence rates of adverse events of special interest for covid-19 vaccines in eight countries: multinational network cohort study | The BMJ
https://www.bmj.com/content/373/bmj.n1435?utm_source=twitter&utm_medium=social&utm_term=hootsuite&utm_content=sme&utm_campaign=usage
Largest, Most Extensive Study Of Adverse Events Background Rates Can Inform COVID Vaccines Safety Monitoring Efforts
https://www.dbmi.columbia.edu/aesi-background-rates-study/
U.S. Population-Based background incidence rates of medical conditions for use in safety assessment of COVID-19 vaccines - ScienceDirect
https://www.sciencedirect.com/science/article/pii/S0264410X21005788?via%3Dihub
Adverse events following COVID‐19 mRNA vaccines: A systematic review of cardiovascular complication, thrombosis, and thrombocytopenia - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10022421/
,1,New Yale Study: Vaccine Injured Are Highly Symptomatic with Poor Health (Preprint)
In this online, observational, self-reported post-vaccine injured patients the researchers from Yale have gathered and analyzed the kind of symptoms, intensity of symptoms, demography, treatment options, and the psychological status of such patients. Let's review.
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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
References
Post-Vaccination Syndrome: A Descriptive Analysis of Reported Symptoms and Patient Experiences After Covid-19 Immunization | medRxiv
https://www.medrxiv.org/content/10.1101/2023.11.09.23298266v1
Brianne Dressen Discusses Vaccine Caused Neurological Injuries - First NIH Study (Vaccine Injury) - YouTube
https://www.youtube.com/watch?v=9XGpe6MTaFg
NIH/NIND Vaccine Injury Study Participant Interview (Dr. Danice Hertz) - YouTube
https://www.youtube.com/watch?v=Bvssp9uA72A
Shaun Barcavage | Patient Interview - Neurological Issues After Vaccination - YouTube
https://www.youtube.com/watch?v=SobqUw7gqhs
Shaun Barcavage | Follow-up Patient Interview - Neurological Issues After Vaccination - YouTube
https://www.youtube.com/watch?v=rX8I5-yG05g
Shaun Barcavage | Third Patient Interview - Neurological Issues After Vaccination - YouTube
https://www.youtube.com/watch?v=TCkqz3kzf4s
Home - React19
https://react19.org/
,1,Muscle Pain - Pain Lecture 2
In 2021 about 56 million US adults experienced chronic pains. 17 million experienced high-impact chronic pains. Pandemic has contributed to a significant new cases. This is the second part of the series to understand what pain is, the anatomy, physiology, pathology, and the management aspects will be covered in this mini-series on pain. Today we will discuss the fundamentals of muscle pain.
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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
URL list from Friday, Nov. 10 2023 17:12 PM
Muscle Pain: Mechanisms and Clinical Significance - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2696782/
Pathophysiology of musculoskeletal pain: a narrative review - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934019/#:~:text=The%20pathogenic%20mechanisms%20of%20musculoskeletal,nervous%20system%20cells%20and%20mediators.
Pathophysiology of skeletal muscle disturbances in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) | Journal of Translational Medicine | Full Text
https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-021-02833-2#Abs1
Cell Membrane Steady Potential - an overview | ScienceDirect Topics
https://www.sciencedirect.com/topics/neuroscience/cell-membrane-steady-potential#:~:text=Decreased%20cell%20potassium%20content%20has,develop%20weakness%20and%20muscle%20paralysis.
,1,What Are Cancers? Cancer Immunology (Part 2) with Prof. Dr. William Murphy
Dr. William J. Murphy is a scientist with extensive experience with immune and the cancer system interactions. Dr. Murphy has graciously offered to help us understand cancer immunology.
Today we will focus more on the CAR-T therapy.
Brief bio of Dr. Murphy:
My research for the past 30 years has centered on translational studies involving modeling cancer-immune system interactions starting with my earlier studies on NK cells and HSCT in mouse models and later at the National Cancer Institute on their role in cancer immunotherapy which then expanded to issues in immunotherapy in general.
If you like this content and want more, I am doing a special lifetime membership offer. Click here:
https://www.drbeen.com/yt-special/
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Buy me a coffee :-) https://www.buymeacoffee.com/DrMobeenSyed
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#drbeen #koolbeens #COVID
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
References with some previous talks
COVID Research - A Talk With Dr. William J. Murphy - YouTube
https://www.youtube.com/watch?v=UdmaZX3ftfY
Dr. William J. Murphy, Ph.D. for UC Davis Health
https://health.ucdavis.edu/team/search/1226/william-murphy---cancer---dermatology---hematology-oncology---pathology---dermatopathology-sacramento
A Possible Role for Anti-idiotype Antibodies in SARS-CoV-2 Infection and Vaccination | NEJM
https://www.nejm.org/doi/full/10.1056/NEJMcibr2113694
Autoimmune Disease after Infection or Vaccine in Some (Article Review of Anti-idiotype Antibodies) - YouTube
https://www.youtube.com/watch?v=kE9UUX7NV5Q
,1,Pain and Why it Becomes Chronic? (Lecture 1)
In 2021 about 56 million US adults experienced chronic pains. 17 million experienced high-impact chronic pains. Pandemic has contributed to a significant new cases. We are starting a series to understand what pain is, the anatomy, physiology, pathology, and the management aspects will be covered in this mini-series on pain. Let's start with pain, pain transduction, pain pathways, and pain modulation in this talk.
If you like this content and want more, I am doing a special lifetime membership offer. Click here:
https://www.drbeen.com/yt-special-p/
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#drbeen #koolbeens #PAIN
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
References
DrBeen.Com
Chronic Pain Among Adults — United States, 2019–2021 | MMWR
https://www.cdc.gov/mmwr/volumes/72/wr/mm7215a1.htm
The Revised IASP definition of pain: concepts, challenges, and compromises - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680716/
Untitled Document
https://www.rnceus.com/ages/nociceptive.htm
The Anatomy and Physiology of Pain - Pain and Disability - NCBI Bookshelf
https://www.ncbi.nlm.nih.gov/books/NBK219252/
Physiology, Enkephalin - StatPearls - NCBI Bookshelf
https://www.ncbi.nlm.nih.gov/books/NBK557764/
Pain Modulation - an overview | ScienceDirect Topics
https://www.sciencedirect.com/topics/medicine-and-dentistry/pain-modulation
The Anatomy and Physiology of Pain - Pain and Disability - NCBI Bookshelf
https://www.ncbi.nlm.nih.gov/books/NBK219252/
Pain Tracts and Sources (Section 2, Chapter 7) Neuroscience Online: An Electronic Textbook for the Neurosciences | Department of Neurobiology and Anatomy - The University of Texas Medical School at Houston
https://nba.uth.tmc.edu/neuroscience/m/s2/chapter07.html
Therapeutic Basis of Clinical Pain Modulation - Kirkpatrick - 2015 - Clinical and Translational Science - Wiley Online Library
https://ascpt.onlinelibrary.wiley.com/doi/pdf/10.1111/cts.12282
Pain Tracts and Sources (Section 2, Chapter 7) Neuroscience Online: An Electronic Textbook for the Neurosciences | Department of Neurobiology and Anatomy - The University of Texas Medical School at Houston
https://nba.uth.tmc.edu/neuroscience/m/s2/chapter07.html
The Anatomy and Physiology of Pain - Pain and Disability - NCBI Bookshelf
https://www.ncbi.nlm.nih.gov/books/NBK219252/#:~:text=The%20pathway%20for%20pain%20transmission,is%20derived%20from%20animal%20studies.
Pain Modulation - an overview | ScienceDirect Topics
https://www.sciencedirect.com/topics/medicine-and-dentistry/pain-modulation
Untitled Document
https://www.rnceus.com/ages/nociceptive.htm
Physiology, Enkephalin - StatPearls - NCBI Bookshelf
https://www.ncbi.nlm.nih.gov/books/NBK557764/
Moving Beyond Pain as the Fifth Vital Sign and Patient Satisfaction Scores to Improve Pain Care in the 21st Century - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5878703/
,1,What Are Cancers? Cancer Immunology with Prof. Dr. William Murphy
Dr. William J. Murphy is a scientist with extensive experience with immune and the cancer system interactions. Dr. Murphy has graciously offered to help us understand cancer immunology.
In the session today we will address as many of the following points as possible:
What is cancer? Basic tumor biology and misconceptions
Causes of cancer, changing demographics
Different cancer types and outcomes
Invasion and metastasis
Factors affecting incidence and progression (and outcome)
How diagnose and treat (past and present)- factors affecting decisions
How do we study cancer in the research laboratory? Limitations
Immunology of cancer
Brief bio of Dr. Murphy:
My research for the past 30 years has centered on translational studies involving modeling cancer-immune system interactions starting with my earlier studies on NK cells and HSCT in mouse models and later at the National Cancer Institute on their role in cancer immunotherapy which then expanded to issues in immunotherapy in general.
If you like this content and want more, I am doing a special lifetime membership offer. Click here:
https://www.drbeen.com/yt-special/
Want to support this work?:
Buy me a coffee :-) https://www.buymeacoffee.com/DrMobeenSyed
Become my patron: https://www.patreon.com/mobeensyed?fan_landing=true
PayPal: https://paypal.me/mobeensyed?locale.x=en_US
#drbeen #koolbeens #COVID
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
References with some previous talks
COVID Research - A Talk With Dr. William J. Murphy - YouTube
https://www.youtube.com/watch?v=UdmaZX3ftfY
Dr. William J. Murphy, Ph.D. for UC Davis Health
https://health.ucdavis.edu/team/search/1226/william-murphy---cancer---dermatology---hematology-oncology---pathology---dermatopathology-sacramento
A Possible Role for Anti-idiotype Antibodies in SARS-CoV-2 Infection and Vaccination | NEJM
https://www.nejm.org/doi/full/10.1056/NEJMcibr2113694
Autoimmune Disease after Infection or Vaccine in Some (Article Review of Anti-idiotype Antibodies) - YouTube
https://www.youtube.com/watch?v=kE9UUX7NV5Q
,1,More Legal COVID Thoughts With Paul Bork
As promised Paul Bork will discuss the COVID related legal landscape. We will continue this series of legal landscape review if you liked it.
If you like this content and want more, I am doing a special lifetime membership offer. Click here:
https://www.drbeen.com/yt-special-p/
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#drbeen #koolbeens #COVID
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
,1,FDA Finds Seizures Signal in 2-5 Year Old After COVID-19 mRNA Vaccines
We are aware of the vaccine associated myocarditis/pericarditis. In this newly published study (preprint) funded by FDA there is a presence of a new safety signal for vaccinated children between the age of 2-5 years - seizures/convulsions. Let's review this study.
If you like this content and want more, I am doing a special lifetime membership offer. Click here:
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#drbeen #koolbeens #COVID
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
References:
DrBeen: Medical Education Online
https://www.drbeen.com/
Safety of Monovalent BNT162b2 (Pfizer-BioNTech), mRNA-1273 (Moderna), and NVX-CoV2373 (Novavax) COVID-19 Vaccines in US Children Aged 6 months to 17 years | medRxiv
https://www.medrxiv.org/content/10.1101/2023.10.13.23296903v1
Safety of Monovalent BNT162b2 (Pfizer-BioNTech), mRNA-1273 (Moderna), and NVX-CoV2373 (Novavax) COVID-19 Vaccines in US Children Aged 6 months to 17 years
https://www.medrxiv.org/content/10.1101/2023.10.13.23296903v1.full.pdf
CDC Approves COVID-19 Vaccines for Kids Under 5 Years of Age—What Parents Should Know - Stanford Medicine Children’s Health BlogHealthier, Happy Lives Blog
https://healthier.stanfordchildrens.org/en/covid-19-vaccines-for-kids-under-5-years-of-age-what-parents-should-know/#:~:text=On%20June%2018%2C%202022%2C%20the,are%20newly%20eligible%20for%20vaccination.
,1,DoD Settles COVID Vaccine Mandate Lawsuits for $1.8 Million
An excerpt from the article: "A judge awarded Liberty Counsel, the firm representing plaintiffs in Navy SEALs 1-26 v. Biden and Colonel Financial Management Officer, et al. v. Austin, $1.8 million to cover legal fees incurred during the cases, which were filed following Defense Secretary Lloyd Austin’s fall 2021 announcement that the COVID-19 vaccine would become mandatory for all troops."
If you like this content and want more, I am doing a special lifetime membership offer. Click here:
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Want to support this work?:
Buy me a coffee :-) https://www.buymeacoffee.com/DrMobeenSyed
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#drbeen #koolbeens #COVID
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
URL list from Thursday, Oct. 12 2023
DoD settles COVID vaccine mandate lawsuits for $1.8 million
https://www.militarytimes.com/news/your-military/2023/10/09/dod-settles-covid-vaccine-mandate-lawsuits-for-18-million/
Could the Supreme Court strike down the military’s vaccination mandate?
https://www.militarytimes.com/news/pentagon-congress/2022/02/18/could-the-supreme-court-strike-down-the-militarys-vaccination-mandate/
Austin ends the military’s COVID-19 vaccine mandate
https://www.militarytimes.com/news/your-military/2023/01/10/austin-ends-the-militarys-covid-19-vaccine-mandate/
FEE SETTLEMENT AGREEMENT AND RELEASE
https://lc.org/PDFs/Attachments2PRsLAs/2023/100423DODSettlementAgreement(signed).pdf
,1,Chit Chat with Dr. Been
Let's have fun chat!
If you like this content and want more, I am doing a special lifetime membership offer. Click here:
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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
Some studies that we might review. I say might because it is a chit chat.
High or low ‘good’ cholesterol may increase dementia risk, study finds
https://www.nbcnews.com/health/heart-health/good-hdl-cholesterol-dementia-risk-rcna118772
Low- and High-Density Lipoprotein Cholesterol and Dementia Risk Over 17 Years of Follow-up Among Members of a Large Health Care Plan | Neurology
https://n.neurology.org/content/early/2023/10/04/WNL.0000000000207876
PII: 0021-9150(96)05802-9
https://tauruspet.med.yale.edu/staff/edm42/IUPUI-website/emorris.tar/emorris/emorris/TransportCourse2006/Papers/Mass%20Transport%20in%20Arteries/LDL-transport-into-arterialwall-Nielsen-Athero1996review.pdf
How 'bad cholesterol' enters artery walls | ScienceDaily
https://www.sciencedaily.com/releases/2019/04/190424153655.htm
Long COVID: Incidence, Impacts, And Implications | Health Affairs
https://www.healthaffairs.org/content/forefront/long-covid-incidence-impacts-and-implications
Long COVID: major findings, mechanisms and recommendations | Nature Reviews Microbiology
https://www.nature.com/articles/s41579-022-00846-2
Distinguishing features of Long COVID identified through immune profiling | Nature
https://www.nature.com/articles/s41586-023-06651-y
,1,California Quietly Repeals Law to Censor Doctors
According to the legal firm HLLI: Governor Newsom and the California State legislature have conceded defeat and repealed AB 2098, a California state law that restricted doctors’ First Amendment free speech rights by threatening disciplinary action against their license for discussing with patients anything about COVID-19 that the State views as “disinformation” or “misinformation.”
Let's review.
If you like this content and want more, I am doing a special lifetime membership offer. Click here:
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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
#drbeen #koolbeens #COVID
URL list from Thursday, Oct. 5 2023 15:25 PM
My previous talks about this law:
https://www.youtube.com/live/KF4_EyFQD7s?si=Mbq7EmooM4KMT0A8
https://www.youtube.com/live/CZ03vz7pi68?si=MMbAx-r2U061UDTe
Bill Text - AB-2098 Physicians and surgeons: unprofessional conduct.
https://leginfo.legislature.ca.gov/faces/billTextClient.xhtml?bill_id=202120220AB2098
(1) Azadeh Khatibi, MD, MS, MPH on X: "And with a stroke of a pen, AB2098, California's COVID medical censorship law, has been quietly repealed by the very same people who had ridiculously wanted it in place. For a year-and-a-half now, I’ve spoken out against this law. Ultimately, I and others sued @GavinNewsom and… https://t.co/iAL5UQtReo" / X
https://twitter.com/azadehkhatibi/status/1708578266209267924?s=46
HLLI Claims Victory with Repeal of California COVID-19 “Disinformation” Statute – Hamilton Lincoln Law Institute
https://hlli.org/hlli-claims-victory-with-repeal-of-california-covid-19-disinformation-statute/
California COVID-19 misinformation law repealed | Credentialing Resource Center
https://credentialingresourcecenter.com/articles/california-covid-19-misinformation-law-repealed
California Repeals COVID Misinformation Law, Bowing to Legal Pressure - Liberty Justice Center
https://libertyjusticecenter.org/newsroom/california-repeals-covid-misinformation-law-bowing-to-legal-pressure/
California's COVID-19 misinformation law is dead
https://www.beckershospitalreview.com/legal-regulatory-issues/californias-covid-19-misinformation-law-is-dead.html
California Misinfo Law Is Dead | MedPage Today
https://www.medpagetoday.com/special-reports/features/106603
California law aiming to curb COVID misinformation blocked by judge | Reuters
https://www.reuters.com/business/healthcare-pharmaceuticals/california-law-aiming-curb-covid-misinformation-blocked-by-judge-2023-01-26/
Doctors who deliver COVID falsehoods no longer committing ‘misconduct’
https://www.sfchronicle.com/health/article/doctors-deliver-covid-falsehoods-no-longer-18402279.php
Newsom repeals CA law that ‘censored’ doctors giving COVID-19 care | Fox News
https://www.foxnews.com/us/newsom-repeals-ca-law-censored-doctors-giving-covid-19-care
,1,Unexpected vaginal bleeding and COVID-19 vaccination in nonmenstruating women
Researchers from Department of Method Development and Analytics, Norwegian Institute of Public Health, Oslo, Norway demonstrated the evidence of increased risk of unexpected vaginal bleeding in non-menstruating women after the mRNA COVID vaccines. Let's review their evidence.
If you like this content and want more, I am doing a special lifetime membership offer. Click here:
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URL list from Friday, Sep. 29 2023
DrBeen: Medical Education Online
https://www.drbeen.com/
Unexpected vaginal bleeding and COVID-19 vaccination in nonmenstruating women | Science Advances
https://www.science.org/doi/10.1126/sciadv.adg1391
New Study Reviewed Vaginal Bleeding In Non-menstruating Women After Covid-19 Vaccination
https://www.forbes.com/sites/ninashapiro/2023/09/29/new-study-reviewed-vaginal-bleeding-in-non-menstruating-women-after-covid-19-vaccination/?sh=561cdeb16f12
Women say COVID vaccines affected their periods. A new study adds to mounting evidence.
https://www.yahoo.com/lifestyle/covid-vaccines-period-changes-011241035.html?guccounter=1
Unexpected vaginal bleeding and COVID-19 vaccination in nonmenstruating women
file:///C:/Users/s_mob/Downloads/sciadv.adg1391.pdf
Defining Menopausal Status in Epidemiologic Studies: A Comparison of Multiple Approaches and their Effects on Breast Cancer Rates - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922404/#:~:text=In%20a%20fourth%20%60combined%20simplistic,premenopausal%20(age%20%3C55%20and%20menstrual
Hormonal IUDs
https://www.plannedparenthood.org/learn/birth-control/iud/hormonal-iuds#:~:text=IUD%20stands%20for%20Intrauterine%20Device,your%20body%20over%20several%20years.
Endometrial Decidualization: The Primary Driver of Pregnancy Health - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312091/#:~:text=Decidualization%20refers%20to%20the%20functional,cells%20(ESCs)%20into%20DSCs.
Decidua - Wikipedia
https://en.wikipedia.org/wiki/Decidua
Frontiers | Endometrial and Menstrual Blood Mesenchymal Stem/Stromal Cells: Biological Properties and Clinical Application
https://www.frontiersin.org/articles/10.3389/fcell.2020.00497/full#:~:text=Endometrial%20stromal%20fibroblasts%20naturally%20differentiate,establishment%20and%20continuation%20of%20pregnancy.
,1,Long COVID: Diagnosis, Differentiation and Treatment with Dr. Bruce Patterson
After a long time, today, we have Dr. Bruce Patterson joining us for a discussion of long COVID, its diagnosis and the management approach. Get ready for an important talk.
Disclosure:
Dr. Mobeen Syed, or DrBeen have no commercial interest with Dr. Bruce Patterson or his organization.
If you like this content and want more, I am doing a special lifetime membership offer. Click here:
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#drbeen #koolbeens #COVID
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
#drbeen #koolbeens #COVID
References:
Science Magazine Article
https://www.science.org/content/article/rare-cases-coronavirus-vaccines-may-cause-long-covid-symptoms
Dr. Patterson's team's papers:
https://www.frontiersin.org/articles/10.3389/fimmu.2021.700782/full
https://www.frontiersin.org/articles/10.3389/fimmu.2021.746021/full
,1,Vaccine Mandates - Judge Shocked and Floored
9th circuit court of appeals' judges is shocked and floored by the Los Angeles Unified School District's continued vaccine mandates. Let's go over the transcript of the YouTube video.
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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
URL list from Friday, Sep. 15 2023
DrBeen: Online Personalized Medical Education
https://www.drbeen.com/
9th Circuit Judges ‘Shocked’ and ‘Floored’ by LAUSD’s Ongoing Covid-19 Vaccine Mandate for Employees – California Globe
https://californiaglobe.com/fr/9th-circuit-judges-shocked-and-floored-by-lausds-ongoing-covid-19-vaccine-mandate-for-employees/
YouTube for which the transcript is presented.
22-55908 Health Freedom Defense Fund, Inc. v. Alberto Carvalho
https://youtu.be/Q0zg5JSJ9Ok?si=j-GyrOvtO-wo7FCg
22-55908 Health Freedom Defense Fund, Inc. v. Alberto Carvalho - YouTube
https://www.youtube.com/watch?v=Q0zg5JSJ9Ok
Vaccines and Related Biological Products Advisory Committee June 15, 2023 Meeting Presentation- Moderna: COVID19 Variant Vaccines
https://www.fda.gov/media/169539/download
Vaccines and Related Biological Products Advisory Committee June 15, 2023 Meeting Presentation- CDC: COVID19 vaccine effectiveness updates
https://www.fda.gov/media/169536/download
Vaccines and Related Biological Products Advisory Committee June 15, 2023 Meeting Presentation- Pfizer: 2023-2024 COVID19 Vaccine Formula- Clinical and Preclinical Supportive Data
https://www.fda.gov/media/169541/download
Vaccines and Related Biological Products Advisory Committee June 15, 2023 Meeting Presentation- Novavax: Data in Support of 2023-2024 Vaccine Update
https://www.fda.gov/media/169540/download
Emergency Use Authorization | FDA
https://www.fda.gov/emergency-preparedness-and-response/mcm-legal-regulatory-and-policy-framework/emergency-use-authorization
FDA Takes Action on Updated mRNA COVID-19 Vaccines to Better Protect Against Currently Circulating Variants | FDA
https://www.fda.gov/news-events/press-announcements/fda-takes-action-updated-mrna-covid-19-vaccines-better-protect-against-currently-circulating
,1,Many Legal COVID Thoughts by Paul Bork
As promised Paul Bork will discuss the COVID related legal landscape. We will continue this series of legal landscape review if you liked it.
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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
,1,Appeals Court Judge Shocked by Vaccine Mandates
9th circuit court of appeals' judges seem to be floored by the Los Angeles Unified School District's continued vaccine mandates. Let's listen in to the arguments and the absurd mandates by the LAUSD.
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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
URL list from Friday, Sep. 15 2023
DrBeen: Online Personalized Medical Education
https://www.drbeen.com/
22-55908 Health Freedom Defense Fund, Inc. v. Alberto Carvalho
https://youtu.be/Q0zg5JSJ9Ok?si=j-GyrOvtO-wo7FCg
22-55908 Health Freedom Defense Fund, Inc. v. Alberto Carvalho - YouTube
https://www.youtube.com/watch?v=Q0zg5JSJ9Ok
Vaccines and Related Biological Products Advisory Committee June 15, 2023 Meeting Presentation- Moderna: COVID19 Variant Vaccines
https://www.fda.gov/media/169539/download
Vaccines and Related Biological Products Advisory Committee June 15, 2023 Meeting Presentation- CDC: COVID19 vaccine effectiveness updates
https://www.fda.gov/media/169536/download
Vaccines and Related Biological Products Advisory Committee June 15, 2023 Meeting Presentation- Pfizer: 2023-2024 COVID19 Vaccine Formula- Clinical and Preclinical Supportive Data
https://www.fda.gov/media/169541/download
Vaccines and Related Biological Products Advisory Committee June 15, 2023 Meeting Presentation- Novavax: Data in Support of 2023-2024 Vaccine Update
https://www.fda.gov/media/169540/download
,1,Let's Review the Process for FDA Booster Authorization for 2023/2024
Let's review the approach FDA took to authorize/approve the monovalent boosters for 2023 fall season. It is interesting to see the vaccine efficacy duration and the data used to get the authorization.
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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
URL list from Thursday, Sep. 14 2023
Vaccines and Related Biological Products Advisory Committee June 15, 2023 Meeting Announcement - 06/15/2023 | FDA
https://www.fda.gov/advisory-committees/advisory-committee-calendar/vaccines-and-related-biological-products-advisory-committee-june-15-2023-meeting-announcement
Vaccines and Related Biological Products Advisory Committee June 15, 2023 Meeting Briefing Document- FDA
https://www.fda.gov/media/169378/download
Vaccines and Related Biological Products Advisory Committee June 15, 2023 Meeting Presentation- CDC: COVID19 vaccine effectiveness updates
https://www.fda.gov/media/169536/download
Vaccines and Related Biological Products Advisory Committee June 15, 2023 Meeting Presentation- Pfizer: 2023-2024 COVID19 Vaccine Formula- Clinical and Preclinical Supportive Data
https://www.fda.gov/media/169541/download
Vaccines and Related Biological Products Advisory Committee June 15, 2023 Meeting Presentation- Novavax: Data in Support of 2023-2024 Vaccine Update
https://www.fda.gov/media/169540/download
FDA Takes Action on Updated mRNA COVID-19 Vaccines to Better Protect Against Currently Circulating Variants | FDA
https://www.fda.gov/news-events/press-announcements/fda-takes-action-updated-mrna-covid-19-vaccines-better-protect-against-currently-circulating
,1,Court - FDA Wrong on Ivermectin Posts
Excerpts from the decision: "FDA is not a physician. It has authority to inform, announce, and apprise—but not to endorse, denounce, or advise."
"Even tweet-sized doses of personalized medical advice are beyond FDA’s statutory authority. We REVERSE the district court’s judgment of dismissal, and we REMAND for further proceedings."
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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
URL list from Thursday, Aug. 24 2023
Part 1: https://www.youtube.com/watch?app=desktop&v=XuoxcBrh4vw
Part 2: https://www.youtube.com/live/dvlY5jmNzmg?si=4sCae_gQpFEy5C8Z
Part 3: https://www.youtube.com/live/0xVa1-daSUk?si=PHFlarjPDrT9BDB4
Court revives doctors' lawsuit saying FDA overstepped its authority with anti-ivermectin campaign | AP News
https://apnews.com/article/coronavirus-ivermectin-fda-doctors-lawsuit-bbc8d4fc726c08940ae4b0dad70170e0
22-40802 Apter v. Dept of Health & Human Svc, August 8, 2023 - YouTube
https://www.youtube.com/watch?v=bxdQti31CQY
Why You Should Not Use Ivermectin to Treat or Prevent COVID-19 | FDA
https://www.fda.gov/consumers/consumer-updates/why-you-should-not-use-ivermectin-treat-or-prevent-covid-19
AMA, APhA, ASHP statement on ending use of ivermectin to treat COVID-19 | American Medical Association
https://www.ama-assn.org/press-center/press-releases/ama-apha-ashp-statement-ending-use-ivermectin-treat-covid-19
Why ivermectin should not be used to prevent or treat COVID-19 | American Medical Association
https://www.ama-assn.org/delivering-care/public-health/why-ivermectin-should-not-be-used-prevent-or-treat-covid-19
American Medical Association, Other Groups Warn Against Ivermectin Use for Coronavirus
https://www.usnews.com/news/health-news/articles/2021-09-02/american-medical-association-other-groups-warn-against-ivermectin-use-for-coronavirus
What the FDA wants doctors to tell patients asking for ivermectin | American Medical Association
https://www.ama-assn.org/delivering-care/public-health/what-fda-wants-doctors-tell-patients-asking-ivermectin
Microsoft Word - Ivermectin Letter Final.docx
https://www.ushp.org/resources/Documents/Statements/Ivermectin%20USHP%20Letter%20Final.pdf
Federal court says pharmacists can use independent judgement in filling prescriptions - ABC 6 News - kaaltv.com
https://www.kaaltv.com/news/federal-court-says-pharmacists-can-use-independent-judgement-in-filling-prescriptions/
Bill Text - AB-2098 Physicians and surgeons: unprofessional conduct.
https://leginfo.legislature.ca.gov/faces/billNavClient.xhtml?bill_id=202120220AB2098
Michael Crichton Explains Why There Is ‘no Such Thing as Consensus Science’ | American Enterprise Institute - AEI
https://www.aei.org/carpe-diem/michael-crichton-explains-why-there-is-no-such-thing-as-consensus-science/#:~:text=The%20greatest%20scientists%20in%20history,%2C%20it%20isn't%20consensus.
Michael Crichton - The Official Site of Michael Crichton
https://www.michaelcrichton.com/
,1,COVID Stats - Why is CDC/UK/World Going Crazy?
Our resident statistician Paul Bork discusses the new variants and their impact. Let's listen in.
If you like this content and want more, I am doing a special lifetime membership offer. Click here:
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#drbeen #koolbeens #COVID
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
,1,FDA In Court on Ivermectin Statements - Part 3/Last
FDA says to the court, "It's not the role of the courts to fact check the FDA’s scientific statements meant to further their mission to protect the public from dangerous uses of drugs."
Previous talks
At 31:26 FDA says: "FDA is clearly acknowledging that doctors have the authority to prescribe human Ivermectin to treat covid so they are not interfering with the authority of doctors to prescribe drugs or to practice medicine."
If you like this content and want more, I am doing a special lifetime membership offer. Click here:
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#drbeen #koolbeens #COVID
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
URL list from Thursday, Aug. 24 2023
Part 1: https://www.youtube.com/watch?app=desktop&v=XuoxcBrh4vw
Part 2: https://www.youtube.com/live/dvlY5jmNzmg?si=FJ7AfuYAH0mQXqUl
22-40802 Apter v. Dept of Health & Human Svc, August 8, 2023 - YouTube
https://www.youtube.com/watch?v=bxdQti31CQY
Why You Should Not Use Ivermectin to Treat or Prevent COVID-19 | FDA
https://www.fda.gov/consumers/consumer-updates/why-you-should-not-use-ivermectin-treat-or-prevent-covid-19
AMA, APhA, ASHP statement on ending use of ivermectin to treat COVID-19 | American Medical Association
https://www.ama-assn.org/press-center/press-releases/ama-apha-ashp-statement-ending-use-ivermectin-treat-covid-19
Why ivermectin should not be used to prevent or treat COVID-19 | American Medical Association
https://www.ama-assn.org/delivering-care/public-health/why-ivermectin-should-not-be-used-prevent-or-treat-covid-19
American Medical Association, Other Groups Warn Against Ivermectin Use for Coronavirus
https://www.usnews.com/news/health-news/articles/2021-09-02/american-medical-association-other-groups-warn-against-ivermectin-use-for-coronavirus
What the FDA wants doctors to tell patients asking for ivermectin | American Medical Association
https://www.ama-assn.org/delivering-care/public-health/what-fda-wants-doctors-tell-patients-asking-ivermectin
Microsoft Word - Ivermectin Letter Final.docx
https://www.ushp.org/resources/Documents/Statements/Ivermectin%20USHP%20Letter%20Final.pdf
Federal court says pharmacists can use independent judgement in filling prescriptions - ABC 6 News - kaaltv.com
https://www.kaaltv.com/news/federal-court-says-pharmacists-can-use-independent-judgement-in-filling-prescriptions/
Bill Text - AB-2098 Physicians and surgeons: unprofessional conduct.
https://leginfo.legislature.ca.gov/faces/billNavClient.xhtml?bill_id=202120220AB2098
Michael Crichton Explains Why There Is ‘no Such Thing as Consensus Science’ | American Enterprise Institute - AEI
https://www.aei.org/carpe-diem/michael-crichton-explains-why-there-is-no-such-thing-as-consensus-science/#:~:text=The%20greatest%20scientists%20in%20history,%2C%20it%20isn't%20consensus.
Michael Crichton - The Official Site of Michael Crichton
https://www.michaelcrichton.com/
,1,FDA In Court on Ivermectin Statements - Part 2
At 31:26 FDA says: "FDA is clearly acknowledging that doctors have the authority to prescribe human Ivermectin to treat COVID so they are not interfering with the authority of doctors to prescribe drugs or to practice medicine."
If you like this content and want more, I am doing a special lifetime membership offer. Click here:
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#drbeen #koolbeens #COVID
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
URL list from Thursday, Aug. 24 2023
Part 1: https://www.youtube.com/watch?app=desktop&v=XuoxcBrh4vw
22-40802 Apter v. Dept of Health & Human Svc, August 8, 2023 - YouTube
https://www.youtube.com/watch?v=bxdQti31CQY
Why You Should Not Use Ivermectin to Treat or Prevent COVID-19 | FDA
https://www.fda.gov/consumers/consumer-updates/why-you-should-not-use-ivermectin-treat-or-prevent-covid-19
AMA, APhA, ASHP statement on ending use of ivermectin to treat COVID-19 | American Medical Association
https://www.ama-assn.org/press-center/press-releases/ama-apha-ashp-statement-ending-use-ivermectin-treat-covid-19
Why ivermectin should not be used to prevent or treat COVID-19 | American Medical Association
https://www.ama-assn.org/delivering-care/public-health/why-ivermectin-should-not-be-used-prevent-or-treat-covid-19
American Medical Association, Other Groups Warn Against Ivermectin Use for Coronavirus
https://www.usnews.com/news/health-news/articles/2021-09-02/american-medical-association-other-groups-warn-against-ivermectin-use-for-coronavirus
What the FDA wants doctors to tell patients asking for ivermectin | American Medical Association
https://www.ama-assn.org/delivering-care/public-health/what-fda-wants-doctors-tell-patients-asking-ivermectin
Microsoft Word - Ivermectin Letter Final.docx
https://www.ushp.org/resources/Documents/Statements/Ivermectin%20USHP%20Letter%20Final.pdf
Federal court says pharmacists can use independent judgement in filling prescriptions - ABC 6 News - kaaltv.com
https://www.kaaltv.com/news/federal-court-says-pharmacists-can-use-independent-judgement-in-filling-prescriptions/
Bill Text - AB-2098 Physicians and surgeons: unprofessional conduct.
https://leginfo.legislature.ca.gov/faces/billNavClient.xhtml?bill_id=202120220AB2098
Michael Crichton Explains Why There Is ‘no Such Thing as Consensus Science’ | American Enterprise Institute - AEI
https://www.aei.org/carpe-diem/michael-crichton-explains-why-there-is-no-such-thing-as-consensus-science/#:~:text=The%20greatest%20scientists%20in%20history,%2C%20it%20isn't%20consensus.
Michael Crichton - The Official Site of Michael Crichton
https://www.michaelcrichton.com/
,1,FDA Quips and Science in Court - Part 1
In this court case FDA says and I quote, " FDA was not regulating the off-label use of drugs. These statements are not regulations they have no legal consequences they don't prohibit doctors from prescribing Ivermectin to treat covid or for any other purpose. Quite to the contrary there are three instances I'd like to point the court to in the record that show that FDA explicitly recognizes that doctors do have the authority to prescribe ivermectin to treat covid."
If you like this content and want more, I am doing a special lifetime membership offer. Click here:
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Buy me a coffee :-) https://www.buymeacoffee.com/DrMobeenSyed
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#drbeen #koolbeens #COVID
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
URL list from Friday, Aug. 11 2023
22-40802 Apter v. Dept of Health & Human Svc, August 8, 2023 - YouTube
https://www.youtube.com/watch?v=bxdQti31CQY
Oral Argument Recordings
http://www.ca5.uscourts.gov/oral-argument-information/oral-argument-recordings
ca5.uscourts.gov/OralArgRecordings/22/22-40802_8-8-2023.mp3
https://www.ca5.uscourts.gov/OralArgRecordings/22/22-40802_8-8-2023.mp3
Why You Should Not Use Ivermectin to Treat or Prevent COVID-19 | FDA
https://www.fda.gov/consumers/consumer-updates/why-you-should-not-use-ivermectin-treat-or-prevent-covid-19
What the FDA wants doctors to tell patients asking for ivermectin | American Medical Association
https://www.ama-assn.org/delivering-care/public-health/what-fda-wants-doctors-tell-patients-asking-ivermectin
Why ivermectin should not be used to prevent or treat COVID-19 | American Medical Association
https://www.ama-assn.org/delivering-care/public-health/why-ivermectin-should-not-be-used-prevent-or-treat-covid-19
,1,New COVID Variant and Unlosable FDA Suit?
Our resident statistician Paul Bork discusses the new variants and their impact. Let's listen in.
If you like this content and want more, I am doing a special lifetime membership offer. Click here:
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#drbeen #koolbeens #COVID
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
,1,FDA In Court For the Ivermectin Statements
In this court case FDA says and I quote, "FDA was not regulating the off-label use of drugs. These statements are not regulations they have no legal consequences they don't prohibit doctors from prescribing Ivermectin to treat COVID or for any other purpose. Quite to the contrary there are three instances I'd like to point the court to in the record that show that FDA explicitly recognizes that doctors do have the authority to prescribe ivermectin to treat COVID."
If you like this content and want more, I am doing a special lifetime membership offer. Click here:
https://www.drbeen.com/yt-special-p/
Want to support this work?:
Buy me a coffee :-) https://www.buymeacoffee.com/DrMobeenSyed
Become my patron: https://www.patreon.com/mobeensyed?fan_landing=true
PayPal: https://paypal.me/mobeensyed?locale.x=en_US
My substack: https://mobeensyedmd.substack.com/
#drbeen #koolbeens #COVID
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
URL list from Friday, Aug. 11 2023
22-40802 Apter v. Dept of Health & Human Svc, August 8, 2023 - YouTube
https://www.youtube.com/watch?v=bxdQti31CQY
Oral Argument Recordings
http://www.ca5.uscourts.gov/oral-argument-information/oral-argument-recordings
ca5.uscourts.gov/OralArgRecordings/22/22-40802_8-8-2023.mp3
https://www.ca5.uscourts.gov/OralArgRecordings/22/22-40802_8-8-2023.mp3
Why You Should Not Use Ivermectin to Treat or Prevent COVID-19 | FDA
https://www.fda.gov/consumers/consumer-updates/why-you-should-not-use-ivermectin-treat-or-prevent-covid-19
What the FDA wants doctors to tell patients asking for ivermectin | American Medical Association
https://www.ama-assn.org/delivering-care/public-health/what-fda-wants-doctors-tell-patients-asking-ivermectin
Why ivermectin should not be used to prevent or treat COVID-19 | American Medical Association
https://www.ama-assn.org/delivering-care/public-health/why-ivermectin-should-not-be-used-prevent-or-treat-covid-19
(27) Chief Nerd on Twitter: "5) In the Most Disturbing Admission, FDA Attorney Ashley Cheung Honold Says the FDA is ‘Held Accountable by the Political Process’ “The public can elect its government officials and FDA…have politically accountable heads of the agency who are held accountable by the political… https://t.co/RP4YY0ZUHy" / X
https://twitter.com/TheChiefNerd/status/1688966725117612040
,1,NIH/NIND Vaccine Injury Study - Participant Interview (Dr. Danice Hertz)
Study preprint: https://www.medrxiv.org/content/10.1101/2022.05.16.22274439v1
About Dr. Hertz: Danice Hertz MD is a retired gastroenterologist in Los Angeles, California. She received a BA in Biology from UC San Diego. She attended UCLA medical school and completed an internal medicine residency and gastroenterology fellowship at UCLA as well. She is board certified in both fields. She practiced gastroenterology in Santa Monica, California for 33 years and retired in October of 2020.
If you like this content and want more, I am doing a special lifetime membership offer. Click here:
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#drbeen #koolbeens #COVID
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
