Muscle Abnormalities Worsen in Post Exertional Malaise

Muscle Abnormalities Worsen in Post Exertional Malaise In this amazing study the Dutch researchers used muscle biopsies in the long COVID patients suffering from post-exertional malaise. They found that the muscle phenotype had changed resulting in lower excercise capacity. They also found mitochondrial function issues, and local amyloid accumulation. Macrophages and CD3+ T cells were also infiltrated in the muscle tissues. Let's review. If you like this content and want more, click here: https://www.drbeen.com/ Want to support this work?: Become my patron: https://www.patreon.com/mobeensyed?fan_landing=true PayPal: https://paypal.me/mobeensyed?locale.x=en_US #drbeen #koolbeens #COVID Disclaimer: This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional. Muscle abnormalities worsen after post-exertional malaise in long COVID - Nature Communications https://www.nature.com/articles/s41467-023-44432-3 A discovery in the muscles of long COVID patients may explain exercise troubles https://www.npr.org/sections/health-shots/2024/01/09/1223077307/long-covid-exercise-post-exertional-malaise-mitochondria A central role for amyloid fibrin microclots in long COVID/PASC: origins and therapeutic implications - PubMed https://pubmed.ncbi.nlm.nih.gov/35195253/ Amyloidosis: Definition of Amyloid and Amyloidosis, Classification Systems, Systemic Amyloidoses https://emedicine.medscape.com/article/335414-overview Treating the Most Disruptive Symptoms First and Preventing Worsening of Symptoms | Clinical Care of Patients | Healthcare Providers | Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) | CDC https://www.cdc.gov/me-cfs/healthcare-providers/clinical-care-patients-mecfs/treating-most-disruptive-symptoms.html Muscle Fatigue: Lactic Acid or Inorganic Phosphate the Major Cause? | Physiology https://journals.physiology.org/doi/full/10.1152/physiologyonline.2002.17.1.17#:~:text=Intracellular%20acidosis%20due%20mainly%20to,cause%20of%20skeletal%20muscle%20fatigue. Science Fact or Science Fiction? Lactic Acid Buildup Causes Muscle Fatigue and Soreness | Pfizer https://www.pfizer.com/news/articles/science_fact_or_science_fiction_lactic_acid_buildup_causes_muscle_fatigue_and_soreness Glycolysis - Wikipedia https://en.wikipedia.org/wiki/Glycolysis Human Skeletal Muscle Fiber Type Classifications https://academic.oup.com/ptj/article/81/11/1810/2857618 Muscle Fiber Type Transitions with Exercise Training: Shifting Perspectives https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473039/ Muscle Hypertrophy - an overview | ScienceDirect Topics https://www.sciencedirect.com/topics/medicine-and-dentistry/muscle-hypertrophy Muscle abnormalities worsen after post-exertional malaise in long COVID - Nature Communications https://www.nature.com/articles/s41467-023-44432-3 A discovery in the muscles of long COVID patients may explain exercise troubles https://www.npr.org/sections/health-shots/2024/01/09/1223077307/long-covid-exercise-post-exertional-malaise-mitochondria